NephroVir®
A biomarker that combines the power of AI and Immunology to predict the risk of BKv-associated nephropathy in kidney transplant recipients.
Understanding BK-v Nephropathy
BK-virus nephropathy is a major infectious complication in kidney transplantation without specific antiviral treatment. It is secondary to the replication of the BK virus within the kidney graft. It affects up to 10% of transplant patients, typically occurring in the first 24 months post-transplant, and is responsible for the loss of the transplanted kidney in more than 50% of cases. It is the first infectious cause of kidney graft loss.
FAQ
What is NephroVir®?
NephroVir is a medical device combining immunology and artificial intelligence to provide a personalized risk assessment for BK-v nephropathy in kidney transplant recipients with BKv viremia.
How do doctors use NephroVir® in their practice?
NephroVir is provided as a diagnostic kit and a web application. Doctors input the result of the kit and two other clinical parameters of patients into the web application to generate a risk assessment report on BK virus-associated nephropathy. This allows doctors to adapt the immunosupression treatment to prevent BK-v nephropathy and graft loss.
What are the benefits of NephroVir® for kidney transplant patients?
NephroVir allows a precise and early stratification of the risk of BKv-associated nephropathy in patients with BKv-viremia. The diagnosis of BKv-associated nephropathy is often late and involves an invasive kidney biopsy procedure. Identifying a high risk following a single blood testing will allow for an early adaptation of the immunosuppressive treatment to prevent graft loss. Conversely, NephroVir may help to avoid unnecessary reduction of immunosuppressive therapy, which may favor allogeneic graft rejection. NephroVir also allows monitoring of the risk of Bkv nephropathy after therapeutic adaptation.
Where can healthcare professionals and institutions access NephroVir®?
Healthcare professionals interested in using NephroVir can inquire at contact@bluetheris.com